L-Glutamine Powder will help in replenishing the decreased level of glutamine in the body and also helps in intense workouts.
What Is L-Glutamine?
L-Glutamine is one of the most common amino acids in the blood stream. It is mainly found in very high concentrations in skeletal muscles, liver, lungs, brains and the gastrointestinal tissues. It is the skeletal muscle that contains the greatest concentration of glutamine which has up to almost 60% of the total body glutamine stores. The muscles are the first and the primary storage depot and the exporter of this amino acid to the other tissues. It is the gastro intestinal tract that has greater use of glutamine in the body. Because it helps in providing the primary fuel for the cells that absorbs the nutrients that line the small intestine walls. Glutamine contains 19% of nitrogen which makes it a primary transporter of nitrogen in the muscle cells.
Glutamine is a natural amino acid that is present in the body. Various stressors like trauma, chemotherapy, malnutrition and infections and a lot more can bring a great change in the normal functioning of the enterocytes. When the gut permeability is impaired it allows large protein molecules and also mounts an immune reaction against them which can ultimately result in food allergies. This was proved in a number of studies that was conducted in the animals. When the animals which had hyper permeability of the intestine were induced, the addition of glutamine showed improvement in the permeability function and also the gut immune function.
More about L-Glutamine
There are few circumstances that the body requires more of glutamine than the amount that is in the body and can supply it by the diet. In certain cases of metabolic stress, glutamine reaches the bloodstream from the muscles and is transported to the tissues. The glutamine concentrations in the skeletal muscles can be affected by any of the infection, injury, stress which is for a chronic period of time, malnutrition and also the use of glucocorticoids. In such conditions a glutamine supplementation will benefits the required structures and in turn benefit the functions. It takes 6 days for the glutamine to return to normal levels. Studies have shown that L-glutamine supplementation can decrease the breakdown of the muscle and also improve the protein metabolism in the body.
A supplementation of glutamine will benefit the gastrointestinal health and also helps in healing of wounds, immune health. It also support the nutrition for individuals who are undergoing radiation and chemotherapy.
Importance Of Having L-Glutamine Powder – Benefits
Though L-Glutamine Powder is more commonly taken by the body builders, it isn’t necessary for them alone. L-Glutamine is necessary for intestinal functions and also helps in immune response as well. When glutamine is synthesized in the skeletal muscle it is then released in the blood stream and is transported to the liver, kidney and the small intestine and also the cells of the immune system where it has major roles to play.
L-Glutamine is also used by WBC’s in the blood and also helps and contributes in the functioning of the immune system. If you are suffering from any conditions that makes the body unable to produce Glutamine, the supplement can help a lot in adjusting the levels of glutamine in the body. Turning ill or losing lean muscle is the main signs of glutamine deficiency in the body.
Treatment With L-Glutamine
Glutamine has been directly linked to protein synthesis. It helps in the prevention of the muscle from being eaten up or catabolised to provide Glutamine to the other cells in the body. It also helps in maintaining the cell volume and also hydration, helps in healing wounds and also recovery. Recent studies have shown the glutamine can help in the synthesis of growth hormone in the body. Glutamine also serves to boost the immune system. For the body builders, it is important to compensate the levels of glutamine in the body. L-Glutamine Powder helps in providing glutamine for the intestine too. It has the ability to repair the damages like leaky gut and also helps to maintain the structural integrity of the bowels.
What Can L-Glutamine Do To Our Body?
Glutamine which is an amino acid plays a very major role in protein metabolism, anti cabolism, cell volumizing. It also has the ability to secrete GH- Growth Hormone which will help in metabolism of the fat and also supports the growth of muscles. Glutamine due to its anticatabolism ability helps in preventing the breakdown of it in your muscles.
If you are planning to cut down and get rid of body fat without losing any muscle, glutamine will be beneficial. Glutamine is needed throughout in human bodies for the right performance, the small intestine requires the most and the need is must in immune system too.
It is a must in body builders, for gaining more muscles in the body, but L-Glutamine is must for maintenance effects. L-Glutamine Powder will help in promoting a positive nitrogen balance and will also help in preventing muscle loss.
Few researchers and studies have shown that having just 2 grams of L-Glutamine can increase the level of growth hormone by 400%.
Working Mechanism Of L-Glutamine In Your Body
Glutamine which is one of the most abundant free amino acids in the body is the building blocks of protein. It is produced in the muscles is given to the blood and to the organs that are in need. Glutamine helps in gut functioning, immune system and also in the other essential metabolism in the body, mainly during the time of stress. It also provides carbon and nitrogen which are the fuels in the body. Glutamine is required in the body to make many other chemicals in the body including glucose.
Nitrogen is supplied by glutamine after surgery and after trauma to heal the wounds and also to keep the vital organs functioning. One third of the nitrogen comes from glutamine.
Uses Of L-Glutamine Powder
Recovery from illness and Wound healing
When the body is filled with stress which can be in the form burns, infections, injuries, trauma and other surgical procedures, a hormone called cortisol is released in the bloodstream. When there is a higher level of cortisol it can lower the levels of glutamine in the body. Several researchers and studies have shown that adding glutamine through tube feeding has helped in saving many lives during trauma and for critically ill patients. It is clinically proven that it helps in strengthening the immune system and also reduces the infections mainly the infections that are linked with surgeries.
Glutamine powder also helps in preventing and treating a disease condition called as multiple organ dysfunctions which occurs after shock and has also helped in treating other condition or injuries that occur commonly in patients in the ICU-intensive care unit. L-Glutamine Powder has also helped in recovery from burns – mild to even severe ones.
Role of l-glutamine in treating inflammatory bowel disease
Glutamine is more commonly utilized by the gastro intestinal track. Glutamine helps in protecting the lining of the gastro intestinal tract which is called as mucosa. People who have IBD- ulcerative colitis and Crohn’s diseases do not have much of glutamine in their body. However, more research is required in this field as few reports debate in these facts. However, a prior visit to a doctor is must if you are suffering from Inflammatory Bowel Disease.
Role of L-Glutamine Powder in healing HIV/ AIDS
One of the main symptom or after effect of AIDS/ HIV infection is weight loss. A few studies have reported that those patients be given important nutrients like L-Glutamine Powder, vitamin C and E, selenium, N acetyl cystein will help their intestine to absorb better nutrients and also helps them to gain weight.
Benefit for athletes
Athletes who are practicing for their event especially for marathons will have less amount of L-Glutamine in their bodies and it is common they come up with a cold or a mild fever after an athletic function. Few studies reports that it is because of the role of glutamine that plays a major function in immune system. At the same side, few studies showed that taking glutamine supplements resulted in less infection. However, few more studies and proofs are required to conclude on these topics.
Help of l-glutamine powder in cancer
Nowadays, the number of people who are suffering from cancer is increasing at an alarming rate. Many people who are suffering from cancer are reported of low levels of glutamine. For this reason, glutamine is added to conventional cancer treatments. L-Glutamine Powder is often provided to those malnourished cancer patients who are undergoing chemotherapy and radiation treatments. It is also used in patients who are undergoing bone marrow transplants.
Glutamine helps in the reduction of stomatis which is the inflammation that occurs in the mouth most commonly due to the chemotherapy. It also has the ability to reduce diarrhea which is associated with chemotherapy.
Benefits Of Having L-Glutamine Powder
Glutamine which is the building protein in the body has the capability of making it in the body itself for regular requirements. But in certain cases, it is in need of few extra amounts. As it is an amino acid that is present in the body and is required under certain circumstances, it will have more of benefits.
- It helps in promoting the immune health and Gastro Intestinal health.
- It is a nutrient that plays a major role in wound healing.
- As it is in powder form, it is very easy to mix it in cold or warm water and have it easily.
- It also plays a crucial role in supporting healthy nerve functioning.
- It helps in removing the extra ammonia which is a waste product in the body.
Directions To Use L-Glutamine Powder
It is recommended by experts to have one scoop of L-Glutamine Powder in 8 ounce of water. Have it one to three times daily as per recommendations by your doctor or any qualified health care practioner.
If you are a body builder, you are in need of more L-Glutamine Powder. Have 10-15 grams supplementing 2 to 3 times per day with 5 grams at a time.
You should remember that you receive supply of L-Glutamine through your diet or from other supplements.
If you are already having other supplements make sure that you check the label and confirm.
It is recommended to have L-Glutamine Powder with cold or room temperature liquids or food, Make sure you do not use it with beverages because heat has the ability to destroy the glutamine.
For those children who are below 10 years, do not give L-Glutamine Powder until and unless your pediatrician recommends. For adults, it is important that you speak with your doctors regarding the dose and the safety of L-Glutamine Powder in your body.
If you are having L-Glutamine Powder for reducing the soreness in the mouth glutamine suspension of 4 grams swish and swallow every 4 hrs.
For HIV wasting, 8-40 grams of L-Glutamine is recommended by experts.
The best recommended time to have L-Glutamine Powder is during morning hours after workout, and during night just before your bed time.
What Will Happen If The Level Of Glutamine In The Body Drops Down?
If the body utilizes more of glutamine than your muscles can produce, muscle wasting can occur. This mainly occurs in people who have compromised condition of immune system- eg- HIV/AIDS. Certain types of chemotherapy can also deplete the levels of glutamine in the body. This is where L-Glutamine Powder is going to help you. It will help in providing the right amount of glutamine that is required in the body. During chemotherapy, glutamine helps in preventing chemotherapy related damage by maintaining the vitality of the affected cells and tissues.
Natural Sources Of Glutamine
It includes –
- ricotta cheese,
- raw spinach.
- raw parsley,
Other Available Forms
Glutamine is usually available as L-Glutamine or as a part of a supplement. Apart from the powder form, it is available in capsules, tablets, liquids and powder form.
Warnings While Having L-Glutamine Powder
L-Glutamine Powder is contraindicated in those who are having a history of hypersensitivity to any of the ingredients that are present in the powder pack of L-Glutamine Powder.
Do not consume directly if you are pregnant, consult a health care practitioner if you are planning to have L-Glutamine Powder.
Interactions Of L-Glutamine Powder With Other Medications
There are chances for potential side effects and interactions with the medications; you should take L-Glutamine Powder only under the supervision of a qualified health care provider.
L-Glutamine Powder should not be added with hot items as heat has the ability to destroy glutamine. So have an extra care while storing it- keep it in a dry and cool place.
Glutamine is different from gluten, monosodium glutamate, glutamic acid. Glutamine should not cause any symptoms such as facial pressure, tingling, burning sensation that is associated with monosodium glutamate.
Do not worry if you are gluten sensitive, you can use L-Glutamine Powder without much problems. However, few people can be sensitive to glutamine which is a separate condition to handle from gluten.
L-Glutamine Powder can lead to an increase in the ammonia levels in the body, so having glutamine can decrease the effectiveness of lactulose.
L-Glutamine Powder also has chances to decrease the effectiveness of chemotherapy treatments with certain substance like doxorubicin, methotrexate and 5 flurouracil in patients who are suffering from colon cancer. Few studies also suggest that glutamine supplements may prevent damage of the nerve that is associated with medications called Paclitaxel that is mainly used for cancers in the breast and others.
There are still debates and researchers that are conducted behind the role of glutamine in the cancer patients. Few studies suggest that it stimulates the growth of the tumors. If you are having chemotherapy, do not add on your own, such supplements that contain L-Glutamine Powder without consulting a doctor.
Lactulose can interact with Glutamine which causes moderate interaction. Lactulose aids in decreasing ammonia in the body. Glutamine is converted to ammonia in the system. Taking L-Glutamine Powder along with lactulose has chances to decrease the working of the lactulose.
Few studies show that it might decrease the effect of certain medications for cancer.
Medications that are used to heal and prevent seizures interact with the chemicals in the brain; glutamine can affect the chemicals in the brain and may decrease the effectiveness. The most common medications that are used to prevent seizures are primidone, valproic acid, ganapentin , carbamazepin, phenytoin and others.
Who Should Avoid Having L-Glutamine Powder
People who are suffering with liver disease, kidney disease or Reye syndrome should not have L-Glutamine Powder
People who are presently suffering or have a history of a psychiatric disorder or seizure should use L-Glutamine Powder with caution or under the supervision of a qualified health care professional. Few studies report that having L-Glutamine Powder during such conditions can worsen it.
Many of the elderly people who have decreased kidney function will have to reduce the dose of L-Glutamine Powder if they are having it.
Cautionary Notes While Using L-Glutamine Powder
- Check for the expiry date and make sure that L-Glutamine Powder packet is not of expiry date, if in case if it is an expiry dated product that is delivered in your order, ask for replacements.
- If it has crossed expiry date, do not use it- dispose it in a safe way
- Do not store it in unhygienic places; store it in a safe place, away from reach of children.
- Do not expose it under direct sunlight for a long period of time.
- In case of accidental consumption or overdose of L-Glutamine Powder, do not wait, seek a medical emergency.
- Before starting L-Glutamine Powder, it is important that you meet a qualified health care professional. On appointment, get all your medical documents and do not forget to mention if you have any history of allergy to any substance. This will help your doctor to rule out if L-Glutamine Powder will work safely in your body and suggest you a safe dose according to your age, weight and other systemic conditions.
Side Effects Of Haivng L-Glutamine Powder
There are no reports of side effects of L-Glutamine Powder as glutamine is an amino acid that is present in the body naturally. Just as other supplements, too much and too less is not a good idea to follow. Taking more than the recommended dose of L-Glutamine Powder can have gastro intestinal troubles and so it is necessary to follow only the recommended dose in you.
How To Purchase L-Glutamine Powder?
L-Glutamine Powder is not that easily available normally although few sports stores do store them. It would be comfortable if you order it through the online stores which are reliable, simple and cheaper. Have L-Glutamine Powder from a good company and check the ingredients. Make sure that it is hypo allergic and is free of dairy, yeast, gluten, egg, soy, corn or wheat; it should also be free of artificial color or preservatives.
L-Glutamine Powder is a one of the gentle and effective supplements that will benefit our body. It is neither a steroid nor a medication that has associated side effects or risks, but is a supplement that will help the body with L-Glutamine. This will be truly beneficial if you are an athlete or a sport crazy person; these supplements will help in covering up the deficiencies and ensure that the functioning will be all in the healthy way in the name of L-Glutamine.
I am a Practicing Doctor with over 7 years of experience. I write about healthcare and general wellbeing when i get time. Most of my articles are technical in nature and always factual. I am not so good at stories and these articles are more or less thesis and notes on what i read and understand about medicine. I live in Kerala, a tropical weather state in India which is known for its lagoons, rivers and breathtaking nature.